Article

Sleep and circadian rhythm disruption by NPTX2 loss of function

2023-09-27

Abstract excerpt

Sleep and circadian rhythm disruption (SCRD) is commonly observed in aging, especially in individuals who experience progressive cognitive decline to mild cognitive impairment (MCI) and Alzheimer’s disease (AD). However, precise molecular mechanisms underlying the association between SCRD and aging are not fully understood. Orexin A is a well-characterized “sleep neuropeptide” that is expressed in hypothalamic neu...

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Literature Corpus work: 4838556d-6e65-56a9-a9e0-7b624a483cee
DOI: 10.1101/2023.09.26.559408

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