Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sleep and cardiovascular phenotype in middle-aged hypocretin-deficient narcoleptic mice.

Journal of sleep research - 1 Feb 2014

Silvani Alessandro, Bastianini Stefano, Berteotti Chiara, Cenacchi Giovanna, Leone Ornella, Lo Martire Viviana, Papa Valentina, Zoccoli Giovanna

Abstract excerpt

Narcolepsy with cataplexy (NC) is a lifelong disorder caused by loss of hypothalamic hypocretin/orexin (HCRT) neurones, often starting in childhood. NC patients show altered control of heart rate (HR) and a normotensive non-dipper blood pressure (BP) profile, but the natural history and prognostic significance of these alterations remain unclear. Similar alterations have been observed in HCRT-ataxin-3 transgenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Body Weight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Rate

Share to Neuropeptides

Share to Orexins

Share to Sleep, REM

Share to Wakefulness

Source

Identifiers

PMID: 24033681
DOI: 10.1111/jsr.12081

Genes

HCRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sleep and cardiovascular phenotype in middle-aged hypocretin-deficient narcoleptic mice.PMID 24033681Read ↗

Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins.Semantic proximity Read ↗

Behavioral and sleep/wake characteristics of mice lacking norepinephrine and hypocretin.Semantic proximity Read ↗

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.Semantic proximity Read ↗

The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female <i>Orexin/tTA; TetO-DTA</i> MiceSemantic proximity Read ↗

Sleep, sleep disorders and hypocretin (orexin).Semantic proximity Read ↗

Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders.Semantic proximity Read ↗

The genetics of sleep disorders.Semantic proximity Read ↗

The development of sleep/wake disruption and cataplexy as hypocretin/orexin neurons degenerate in male vs. female Orexin/tTA; TetO-DTA Mice.Semantic proximity Read ↗

Hypocretins/orexins as integrators of physiological information: lessons from mutant animals.Semantic proximity Read ↗

Sleep and circadian rhythm disruption by NPTX2 loss of functionSemantic proximity Read ↗

Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish.Semantic proximity Read ↗

Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.