Article

G-Quadruplex Mediated c-myc Specific Downregulation: A Unique Pathway of the Anticancer Action of Immunomodulator Drugs

2024-05-21

Abstract excerpt

<h4> Abstract </h4> Hydroxychloroquine (HCQ), and chloroquine (CQ) are in the preclinical trial stage for cancer along with their active application in autoimmune diseases and malaria. One of the critical hallmarks of cancer cells is the elevated expression of various oncogenes which promote cancer progression and contribute to poor prognosis. The upstream of the promoter region of these oncogenes often exhibits...

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Literature Corpus work: 47da7a89-a34b-5263-8275-b094dc434441
DOI: 10.1101/2024.05.21.595106

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