Article

TLR4-pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury

2020-03-02

Abstract excerpt

<h4>Background and purpose</h4> Activation of astrocytes contributes to synaptic remodeling, tissue repair and neuronal survival following traumatic brain injury (TBI). However, the mechanisms by which these cells interact to infiltrated inflammatory cells to rewire neuronal networks and repair brain functions remain poorly understood. Here, we explored how TLR4-induced astrocyte activation modified synapses and...

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Literature Corpus work: 47938324-6899-528f-a138-c698478ab6e0
DOI: 10.1101/2020.03.01.972158

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