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Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury

2020-01-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent studies have shown that exosomes act as potent mediators involved in intercellular communication. <bold>Methods: </bold>In the current study, the expression of inflammatory factors and miR-873a-5p in the lesion...

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Literature Corpus work
d246149e-22a3-5ed1-a45b-efb0d356a3b2
DOI
10.21203/rs.2.17543/v2
Open publication

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Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injuryDOI 10.21203/rs.2.17543/v2
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