Article

Variations In Trim5α And Cyclophilin A Genes Among HIV-1 Elite Controllers and Non Controllers In Uganda; A Laboratory-Based Cross-sectional study

2020-06-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Tripartite Motif Containing 5 alpha (TRIM5α), a restriction factor produced ubiquitously in cells and tissues of the body plays an important role in the immune response against HIV. TRIM5α targets the HIV capsid for proteosomal destruction. Cyclophilin A, an intracellular protein has also been reported to influence HIV infectivity in a cell-specific manner. Accor...

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Literature Corpus work: 47196317-da7b-54c9-9eaa-56baffa6e23d
DOI: 10.21203/rs.3.rs-27470/v2

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