Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations in Trim5α and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study.

Retrovirology - 6 Jul 2020

Amanya Sharon Bright, Nyiro Brian, Waswa Francis, Obura Bonniface, Nakaziba Rebecca, Nabulime Eva, Katabazi Ashaba Fred, Nabatanzi Rose, Bayiyana Alice, Mboowa Gerald, Kayongo Alex, Wayengera Misaki, Sande Obondo J

Abstract excerpt

BACKGROUND: Tripartite Motif Containing 5 alpha (TRIM5α), a restriction factor produced ubiquitously in cells and tissues of the body plays an important role in the immune response against HIV. TRIM5α targets the HIV capsid for proteosomal destruction. Cyclophilin A, an intracellular protein has also been reported to influence HIV infectivity in a cell-specific manner. Accordingly, variations in TRIM5α and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Sectional Studies
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Peptidylprolyl Isomerase

Share to Tripartite Motif Proteins

Share to Ubiquitin-Protein Ligases

Share to Uganda

Source

Open in PubMed Open full text

Identifiers

PMID: 32631377
DOI: 10.1186/s12977-020-00527-z
PMCID: PMC7339491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations in Trim5α and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study.PMID 32631377Read ↗

Variations In Trim5α And Cyclophilin A Genes Among HIV-1 Elite Controllers and Non Controllers In Uganda; A Laboratory-Based Cross-sectional studySemantic proximity Read ↗

Variations In Trim5α And Cyclophilin A Genes Among HIV-1 Elite Controllers and Non Controllers In Uganda; A Laboratory-Based Cross-sectional StudySemantic proximity Read ↗

Genetic variations within the CCR5 promoter region among elite and viremic controllers in UgandaSemantic proximity Read ↗

The effect of TRIM5 variants on the susceptibility to HIV-1 infection and disease progression in the Polish population.Semantic proximity Read ↗

IRF5-TNOP3 polymorphisms are associated with elite control of HIV infection: A retrospective study.Semantic proximity Read ↗

Expression profile of host restriction factors in HIV-1 elite controllersSemantic proximity Read ↗

CD4 T-cell transcriptome expression reversal of the lncRNA-mRNA co-expression network in elite controller <i>vs.</i> normal-process HIV patientsSemantic proximity Read ↗

Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size.Semantic proximity Read ↗

The role of tripartite motif family members in mediating susceptibility to HIV-1 infectionSemantic proximity Read ↗

A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort.Semantic proximity Read ↗

Beyond HIV infection: Neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases.Semantic proximity Read ↗

Human TRIM5α: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor FunctioningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.