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Article

IRF5-TNOP3 polymorphisms are associated with elite control of HIV infection: A retrospective study.

Journal of medical virology - 1 Jun 2023

Sepúlveda-Crespo Daniel, Jiménez-Sousa María A, Fernández-Rodíguez Amanda, Muñoz-Fernández María A, Jiménez José Luis, Moreno Santiago, Garcia Felipe, Martínez Isidoro, Benito José M, Rallón Norma, Resino Salvador

Abstract excerpt

IRF5-TNPO3 polymorphisms have previously been related to immune response, and TNPO3 plays a role in human immunodeficiency virus (HIV)-1 infection after nuclear import. Therefore, we analyzed the genetic association between IRF5-TNPO3 polymorphisms and the HIV elite control in long-term nonprogressors (LTNPs). We performed a retrospective cohort study on 183 LTNPs, who were antiretroviral therapy-naïve with CD4+...

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PMID: 37254791
DOI: 10.1002/jmv.28841

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