Article

Methylation Clocks Do Not Predict Age or Alzheimer’s Disease Risk Across Genetically Admixed Individuals

2024-10-18

Abstract excerpt

Epigenetic aging clocks based on DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer’s disease (AD), and environmental and social stressors. However, methylation clocks have not been comprehensively validated in genetically diverse individuals. Here we evaluate a set of first-, second-, and third-generation methylation clocks in 621 AD p...

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Literature Corpus work: 46e8b5e5-2c17-5c8f-8d40-f6cd46edc1fa
DOI: 10.1101/2024.10.16.618588

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