Article

Common DNA sequence variation influences epigenetic aging in African populations

2024-08-26

Abstract excerpt

Aging is associated with genome-wide changes in DNA methylation in humans, facilitating the development of epigenetic age prediction models. However, most of these models have been trained primarily on European-ancestry individuals, and none account for the impact of methylation quantitative trait loci (meQTL). To address these gaps, we analyzed the relationships between age, genotype, and CpG methylation in 3 und...

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Literature Corpus work: 323a57ec-a4fd-514c-b3db-4886ffd2924c
DOI: 10.1101/2024.08.26.608843

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