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Molecular mechanism and clinical significance of Notch3 negative regulation of BRD4 on the growth and survival of esophageal squamous cell carcinoma

2025-10-08

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> The aim of this study was to investigate the expression of bromodomain-containing protein 4 (BRD4) and Notch receptor protein 3 (Notch3) in esophageal squamous cell carcinoma (ESCC) and the effect of their interaction on the growth and survival of ESCC cells. <bold>Methods</bold> The expression of target genes in ESCC and the binding sites between genes were...

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Literature Corpus work
46abe89e-e923-5244-92b6-4ddfbd235b68
DOI
10.21203/rs.3.rs-7554734/v1
Open publication

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