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Article

Molecular pathology and potential therapeutic targets in esophageal basaloid squamous cell carcinoma.

International journal of clinical and experimental pathology - 1 Jan 2015

Saito Tsuyoshi, Mitomi Hiroyuki, Yao Takashi

Abstract excerpt

Basaloid squamous cell carcinoma (BSCC) is a rare and poorly differentiated variant of typical squamous cell carcinoma. Emerging studies show that genetic alterations are more frequent in BSCC than in conventional SCC, and some of which led to the identification of potential therapeutic targets in esophageal BSCC. Approximately half of the esophageal BSCC cases harbor either an EGFR mutation or amplification, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26045734
PMCID: PMC4440043

Genes

EGFR
PTCH1
SFRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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