Article

E3 Ubiquitin Ligase NEDD4L Negatively Regulates Breast Cancer Metastasis By Downregulating SNAI2

2021-10-12

Abstract excerpt

<title>Abstract</title> <p>Background Accumulating evidence demonstrated that the abnormal expression of E3-ubiquitin ligase NEDD4L plays an important role in the biological process of carcinomas. However, its role in breast cancer (BRCA) remains elusive. Methods The expression of <italic>NEDD4L</italic> was analyzed using BRCA datasets from public database. Gene ontology (GO) and Kyoto Encyclopedia of Genes an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 656b4787-3a3c-5da0-ab72-b60388500f18
DOI: 10.21203/rs.3.rs-956231/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

E3 Ubiquitin Ligase NEDD4L Negatively Regulates Breast Cancer Metastasis By Downregulating SNAI2DOI 10.21203/rs.3.rs-956231/v1Read

Unraveling the Potential Role of NEDD4-like E3 Ligases in CancerSemantic proximity Read

Expression and regulatory network of E3 ubiquitin ligase NEDD4 family in cancersSemantic proximity Read

NEDD4 E3 ubiquitin ligases: Promising biomarkers and therapeutic targets for cancerSemantic proximity Read

A Novel Immune-Related LncRNA Pair Model to Predict the Prognosis of Triple-Negative Breast CancerSemantic proximity Read

Downregulation of NEDD4L by EGFR Signaling Promotes the Development of Lung AdenocarcinomaSemantic proximity Read

Identification of a Novel Prognostic Signature for Breast Cancer Based on Post-translational Ubiquitin and Ubiquitin-Like Modification-Related GenesSemantic proximity Read

The Role of PIWIL4, an Argonaute Family Protein, in Breast CancerSemantic proximity Read

Prognostic and Therapeutic Response Analysis of Breast Cancer Based on Post-translational Ubiquitin and Ubiquitin-Like Modification-Related SignatureSemantic proximity Read

Identification of a Novel Prognostic Signature for Breast Cancer Derived from Post-translational Ubiquitin and Ubiquitin-Like Modification-Related GenesSemantic proximity Read

NEDD4 E3 ligase: Functions and mechanism in human cancerSemantic proximity Read

Landscape of tumor suppressor long noncoding RNAs in breast cancerSemantic proximity Read

SPTBN1 and cancer, which links?Semantic proximity Read