Article

Epigenetic dysregulation of the H3K14ac/H3K9me2 axis is associated with malignant transformation and prognosis in colon adenocarcinoma

2026-06-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Histone post-translational modifications (HPTMs) play central roles in chromatin regulation and cancer biology, yet their global and unbiased characterization in colon adenocarcinoma (COAD) remains limited. This gap has hindered a comprehensive understanding of the epigenetic mechanisms that shape tumor-specific transcriptional programs and influence clinical...

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Literature Corpus work: 46a785c7-acc9-5a41-9af5-3f078dc4d116
DOI: 10.21203/rs.3.rs-9763213/v1

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