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Differential H3K4me3 Domains in Normal and Colorectal Cancer Cells Reveal Novel Epigenetic Targets

2025-02-18

Abstract excerpt

Histone H3 trimethylated at lysine 4 (H3K4me3) is a histone mark associated with transcriptionally active genes. H3K4me3 has two types of distribution: a sharp distribution of approximately 500 bp and a broad H3K4me3 domain that may extend 4 kb and longer through the gene body. Most transcribed genes have a narrow H3K4me3 configuration, whereas genes involved in cell identity and tumor suppression have a broad arr...

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Literature Corpus work
f5a460c4-2ded-57a4-9bec-2aab43f29781
DOI
10.20944/preprints202502.1369.v1
Open publication

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Differential H3K4me3 Domains in Normal and Colorectal Cancer Cells Reveal Novel Epigenetic TargetsDOI 10.20944/preprints202502.1369.v1
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