Article

Human airway epithelial cell pH regulatory proteins in cystic fibrosis: Differential expression in nasal and bronchial airway cells

2023-08-23

Abstract excerpt

<h4>Background: </h4> Decreased apical bicarbonate transport into the airway surface liquid (ASL) has been associated with decreased ASL pH in some studies. Low ASL pH can have adverse respiratory effects. However, the human CF epithelium can also normalize ASL pH. We hypothesized that pH regulatory proteins other than the CF transmembrane regulator (CFTR) would be upregulated in the CF epithelium. <h4>Methods: </...

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Literature Corpus work: 469e60cd-d00f-5d29-9702-96c4e2f1225b
DOI: 10.21203/rs.3.rs-3266530/v1

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