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Article

Airway surface liquid pH is not acidic in children with cystic fibrosis

6 Nov 2017

Abstract excerpt

Modulation of airway surface liquid (ASL) pH has been proposed as a therapy for cystic fibrosis (CF). However, evidence that ASL pH is reduced in CF is limited and conflicting. The technical challenges associated with measuring ASL pH in vivo have precluded accurate measurements in humans. In order to address this deficiency, ASL pH was measured in vivo in children using a novel luminescent technology integrated...

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PMID: 29123085
DOI: 10.1038/s41467-017-00532-5

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