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Age-Related Differences in Structure and Function of Nasal Epithelial Cultures From Healthy Children and Elderly People

28 Feb 2022

Abstract excerpt

The nasal epithelium represents the first line of defense against inhaled pathogens, allergens, and irritants and plays a key role in the pathogenesis of a spectrum of acute and chronic airways diseases. Despite age-dependent clinical phenotypes triggered by these noxious stimuli, little is known about how aging affects the structure and function of the airway epithelium that is crucial for lung homeostasis and...

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PMID: 35296085
DOI: 10.3389/fimmu.2022.822437

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