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Article

Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

15 Dec 2020

Abstract excerpt

Abstract Rationale Identification of the specific cell types expressing CFTR (cystic fibrosis [CF] transmembrane conductance regulator) is required for precision medicine therapies for CF. However, a full characterization of CFTR expression in normal human airway epithelia is missing. Objectives To identify the cell types that contribute to CFTR expression and function within the proximal–distal axis of the...

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PMID: 33321047
DOI: 10.1164/rccm.202008-3198oc

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