Article

Genome-wide association study of adolescent-onset depression

2025-09-26

Abstract excerpt

Adolescent depression is a heritable psychiatric condition with rising global prevalence and severe long-term outcomes, yet its biological underpinnings remain poorly understood. We conducted the first genome-wide association study of adolescent-onset depression, comprising 102,428 cases (diagnosis or clinical symptom thresholds) and 286,911 controls, including diverse ancestries. Cross-ancestry meta-analysis iden...

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Literature Corpus work: 469ddcbb-7821-5c66-b549-05bdf97d9efa
DOI: 10.1101/2025.09.26.25335972

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