Article

The role of rare copy number variants in early-onset depression

2025-05-16

Abstract excerpt

<h4>Background</h4> Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later-onset depression. It is also more strongly associated with neurodevelopmental comorbidities and genetic liability to ADHD. Thus, we hypothesised that early...

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Literature Corpus work: 05caafec-cc93-5d4f-b3e6-4b39ba53d129
DOI: 10.1101/2025.05.14.25327601

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