Article

Quantification of multicellular colonization in tumor metastasis using exome sequencing data

2019-02-07

Abstract excerpt

Metastasis is a major cause of cancer-related mortality, and it is essential to understand how metastasis occurs in order to overcome it. One relevant question is the origin of a metastatic tumor cell population. Although the hypothesis of a single-cell origin for metastasis from a primary tumor has long been prevalent, several recent studies using mouse models have supported a multi-cellular origin of metastasis....

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Literature Corpus work: 461c2a70-6092-5a54-8c6a-968506965fab
DOI: 10.1101/542324

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