Article

Transplantation tolerance through the modulation of dendritic cells

2011-01-01

Abstract excerpt

Allogeneic T cell stimulation requires antigen recognition through the T cell receptor and costimulatory signals provided by antigen presenting cells (APCs). For naïve T cells stimulation, interaction between CD28 on T cells and CD80/86 on dendritic cells (DCs) provides an essential costimulatory signal. While, activated effector T cells or memory T cells stimulation is more dependent on costimulation via ICOS on...

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Literature Corpus work: 45c79d6a-fc69-5c77-b5c1-75f326047819
DOI: 10.25560/6203

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