Article
Immune tolerance of skin allograft transplantation induced by immature dendritic cells of a third party carrying donor antigens in mice.
Transplantation proceedings - 1 Mar 2013
Xin H, Yang W, Wang Q, You B, Tong Y, Peng Y
Abstract excerpt
BACKGROUND: Dendritic cells (DCs) are the most powerful antigen-presenting cells in the body. Immature DCs (imDCs) can induce transplantation tolerance. In this study, using a mouse model of skin transplantation. We explored the antigen uptake by imDCs, changes in phenotype and function after antigen loading, as well as survival of skin grafts. METHODS: Mononuclear cells from C57BL/6 mice mixed with a tritiated...
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