Article
CD40 and tolerance induction.
Iranian journal of allergy, asthma, and immunology - 1 Mar 2012
Karimi Mohammad Hossein, Pourfathollah Ali Akbar
Abstract excerpt
CD40 is recognized as a member of tumor necrosis factor receptor super family. It is expressed by the immune and non-immune cells. Its interaction with CD40 ligand (CD154) brings about a regulatory effect on the cellular and humoral immunity. The pathway of CD40-CD154 is influential in various diseases. Investigations on such diseases have revealed dimensional mechanisms whereby this route intensifies host...
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