Article

Dynamic molecular architecture of the synaptonemal complex

2020-02-16

Abstract excerpt

During meiosis, pairing between homologous chromosomes is stabilized by the assembly of a protein lattice known as the synaptonemal complex (SC). The SC ensures the formation of crossovers between homologous chromosomes and also regulates their distribution. However, how the SC regulates crossover formation remains elusive. We isolated an unusual mutation in C. elegans that disrupts crossover interference but not...

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Literature Corpus work: 45bd662d-9dc1-5836-bb55-8b03ebf52aee
DOI: 10.1101/2020.02.16.947804

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