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Article

Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis.

PLoS genetics - 1 Mar 2021

Gordon Spencer G, Kursel Lisa E, Xu Kewei, Rog Ofer

Abstract excerpt

During sexual reproduction the parental homologous chromosomes find each other (pair) and align along their lengths by integrating local sequence homology with large-scale contiguity, thereby allowing for precise exchange of genetic information. The Synaptonemal Complex (SC) is a conserved zipper-like structure that assembles between the homologous chromosomes, bringing them together and regulating exchanges...

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Identifiers

PMID: 33730019
DOI: 10.1371/journal.pgen.1009205
PMCID: PMC7968687

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