Article

Deconvolution of Expression for Nascent RNA Sequencing Data (DENR) Highlights Pre-RNA Isoform Diversity in Human Cells

2021-03-17

Abstract excerpt

Quantification of mature-RNA isoform abundance from RNA-seq data has been extensively studied, but much less attention has been devoted to quantifying the abundance of distinct precursor RNAs based on nascent RNA sequencing data. Here we address this problem with a new computational method called Deconvolution of Expression for Nascent RNA sequencing data (DENR). DENR models the nascent RNA read counts at each loc...

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Literature Corpus work: 59bf710c-32e3-5444-a228-b803ecdfe2f8
DOI: 10.1101/2021.03.16.435537

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