Article

Somatic small-variant calling methods in Illumina DRAGEN™ Secondary Analysis

2023-03-25

Abstract excerpt

We present the DRAGEN™ somatic pipeline for calling small somatic variants from tumor samples, with or without paired normal samples. The DRAGEN somatic variant caller offers 1) a flexible architecture that can be used on a wide array of somatic use cases; 2) built-in noise models enabling robustness against various sources of noise artifacts (mapping, genome context, or sample specific); 3) performance of joint a...

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Literature Corpus work: 45a25ee3-48e2-5923-b17d-16220cc066ef
DOI: 10.1101/2023.03.23.534011

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