Article

Visualization and Modeling of Inhibition of IL-1β and TNF-α mRNA Transcription at the Single-Cell Level

2020-10-16

Abstract excerpt

IL-1β and TNF-α are canonical immune response mediators that play key regulatory roles in a wide range of inflammatory responses to both chronic and acute conditions. Here we employ an automated microscopy platform for the analysis of messenger RNA (mRNA) expression of IL-1β and TNF-α at the single-cell level. The amount of IL-1β and TNF-α mRNA expressed in a human monocytic leukemia cell line (THP-1) is visualize...

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Literature Corpus work: 45815e84-0842-5450-b146-db6f3d745280
DOI: 10.1101/2020.10.16.342576

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