Article

Polygenic Dissection of Synaptic Pruning and Glutamatergic Signaling: Contrasting Mechanisms in ASD and ADHD

2026-01-09

Abstract excerpt

Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) often travel together clinically, yet they present very different pictures in day-to-day life. To see where their biology overlaps and where it parts company, we re-examined the largest available genome-wide association studies for each condition. Three complementary tools—MAGMA for gene and gene-set tests, stratified LD-score regr...

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Literature Corpus work: 0a5a59a3-83b6-5984-9c55-25086c4e86a7
DOI: 10.20944/preprints202601.0692.v1

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Polygenic Dissection of Synaptic Pruning and Glutamatergic Signaling: Contrasting Mechanisms in ASD and ADHDDOI 10.20944/preprints202601.0692.v1Read

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