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From Genes to Circuits: Modeling Neurodevelopmental Disorders

2026-08-13

Abstract excerpt

The genetic architecture of neurodevelopmental disorders (NDDs) is increasingly well described, yet the biological meaning of many variants remains uncertain. A molecular diagnosis may identify the affected gene without explaining how the alteration perturbs brain development or why the same or related variants produce different outcomes. Variant effects are conditioned by dosage, developmental timing, cell identi...

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Literature Corpus work
f8678bd5-3b69-5694-9f9b-81d279d53058
DOI
10.20944/preprints202608.0883.v1
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From Genes to Circuits: Modeling Neurodevelopmental DisordersDOI 10.20944/preprints202608.0883.v1
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