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Checkpoint receptors in circulating γδ T cells can discern the outcome of cancer immunotherapy

2025-01-05

Abstract excerpt

Gamma delta (γδ) T cells are innate-like lymphocytes that in humans can be broadly classified into two main subtypes based on their unique TCRδ chain, Vδ1 and Vδ2. Both subsets have potent anti-tumor properties and the presence of Vδ1 cells in the tumor is often associated with positive prognosis. Herein, we investigated the molecular interplay between immune checkpoint receptors (ICRs), IC blockade (ICB) therapy...

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Literature Corpus work
454f2e24-a9e9-51ca-9354-133305b6e40e
DOI
10.1101/2025.01.05.631352
Open publication

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Checkpoint receptors in circulating γδ T cells can discern the outcome of cancer immunotherapyDOI 10.1101/2025.01.05.631352
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