Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human γδ T cells in the tumor microenvironment: Key insights for advancing cancer immunotherapy

6 Jan 2025

Abstract excerpt

The role of γδ T cells in antitumor responses has gained significant attention due to their major histocompatibility complex (MHC)-independent killing mechanisms, which are functionally distinct from conventional αβ T cells. Notably, γδ tumor-infiltrating lymphocytes (TILs) have been identified as favorable prognostic markers in various cancers. However, the γδ TIL subsets, including Vδ1, Vδ2, and Vδ3, exhibit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39778860
DOI: 10.1016/j.mocell.2025.100177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human γδ T cells in the tumor microenvironment: Key insights for advancing cancer immunotherapyPMID 39778860Read ↗

Deciphering human γδ T cell response in cancer: Lessons from tumor‐infiltrating γδ T cellsSemantic proximity Read ↗

Targeting γδ T Lymphocytes for Cancer Immunotherapy: From Novel Mechanistic Insight to Clinical ApplicationSemantic proximity Read ↗

Role of γδ T Cells in Cancer Progression and Therapy.Semantic proximity Read ↗

γδ T cells in cancer immunotherapy.Semantic proximity Read ↗

Cancer Immunotherapy Using γδT Cells: Dealing with DiversitySemantic proximity Read ↗

Effector Vδ1 γδT cells mediate anti-tumor immunity and are reprogrammed by imatinib in human gastrointestinal stromal tumorSemantic proximity Read ↗

γδ T Cells for Leukemia Immunotherapy: New and Expanding Trends.Semantic proximity Read ↗

A pan-cancer gamma delta T cell repertoireSemantic proximity Read ↗

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancerSemantic proximity Read ↗

NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions.Semantic proximity Read ↗

Prospects for chimeric antigen receptor (CAR) γδ T cells: A potential game changer for adoptive T cell cancer immunotherapy.Semantic proximity Read ↗

Deciphering the Contribution of γδ T Cells to Outcomes in Transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.