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Article

VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2014

Sidibé Adama, Polena Helena, Pernet-Gallay Karin, Razanajatovo Jeremy, Mannic Tiphaine, Chaumontel Nicolas, Bama Soumalamaya, Maréchal Irène, Huber Philippe, Gulino-Debrac Danielle, Bouillet Laurence, Vilgrain Isabelle

Abstract excerpt

Covalent modifications such as tyrosine phosphorylation are associated with the breakdown of endothelial cell junctions and increased vascular permeability. We previously showed that vascular endothelial (VE)-cadherin was tyrosine phosphorylated in vivo in the mouse reproductive tract and that Y685 was a target site for Src in response to vascular endothelial growth factor in vitro. In the present study, we aimed...

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PMID: 24858856
DOI: 10.1152/ajpheart.00774.2013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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