Article

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

2022-06-22

Abstract excerpt

<h4>Summary</h4> Enteroviruses cause a number of medically relevant and widespread human diseases with no approved antiviral therapies currently available. Host-directed therapies present an enticing option for this diverse genus of viruses. We have previously identified the actin histidine methyltransferase SETD3 as a critical host factor physically interacting with the viral protease 2A. Here, we report the 3.5...

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Literature Corpus work: 44f3ed39-cf0c-513d-adde-ea15044240da
DOI: 10.1101/2022.06.22.497068

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