Article

Integrative Structure of Norovirus NS3 Suggests a Role in RNA Transport

2025-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Human noroviruses (HuNoVs) are the leading global cause of non-bacterial gastroenteritis, yet no vaccines or antiviral therapies are currently approved 1 . The viral non-structural protein NS3 is a membrane-bound AAA+ ATPase of superfamily 3 (SF3) with multiple proposed roles in the norovirus replication cycle. However, the structure of NS3, and the mechanisms by which it contributes to genome...

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Literature Corpus work: bd77a902-9f89-517f-a760-839266744a20
DOI: 10.1101/2025.06.17.659504

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