Article

A gene silencing pipeline to interrogate human cDC1 and pDC development and functions

2023-05-18

Abstract excerpt

Type 1 conventional dendritic cells (cDC1s) and plasmacytoid dendritic cells (pDCs) are thought to be critical for anti-tumor or antiviral immunity. In vitro differentiation systems have unlocked the ability to produce large numbers of these cells. However, a method is lacking to systematically identify the cell-intrinsic factors controlling their differentiation and functions that remain therefore poorly understo...

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Literature Corpus work: 44ed1261-aeb5-5a90-943a-07d1c9d60b74
DOI: 10.1101/2023.05.16.540909

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