Article

PANCS-Inhibitors: A rapid method to directly select for protein-protein interaction inhibitors

2026-08-06

Abstract excerpt

Aberrant protein-protein interactions (PPIs) drive myriad diseases. Inhibiting these PPIs often relies on discovering molecules that bind to one of the proteins and hoping that this binding inhibits the PPI. Molecular binder discovery often takes months, but a discovery process that ensures that the resulting molecule not only binds a target protein, but selectively inhibits a target PPI, could dramatically accele...

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Identifiers and source

Literature Corpus work: 448afecc-ccac-572b-8f29-0e58195fa58d
DOI: 10.64898/2026.08.05.743105

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