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Harnessing the 14-3-3 protein–protein interaction network

27 Apr 2024

Abstract excerpt

Protein-protein interactions (PPIs) play a critical role in cellular signaling and represent interesting targets for therapeutic intervention. 14-3-3 proteins integrate many signaling targets via PPIs and are frequently implicated in disease, making them intriguing drug targets. Here, we review the recent advances in the 14-3-3 field. It will discuss the roles 14-3-3 proteins play within the cell, elucidation of...

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PMID: 38685162
DOI: 10.1016/j.sbi.2024.102822

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