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Cellular and Fibrillar Collagen Analyses in an Animal Model of Retinal Detachment-Related Proliferative Vitreoretinopathy Reveals a Defined Transition to Chronic Fibrosis

2022-12-16

Abstract excerpt

<h4>Purpose</h4> Proliferative vitreoretinopathy (PVR) is the most common cause of failure of surgically repaired rhegmatogenous retinal detachment (RRD). Chemically-induced and cell-injection PVR models do not fully simulate the clinical characteristics of PVR in the post-RRD context. There is an unmet need for translational models in which to study mechanisms and treatments specific to RRD-PVR. <h4>Methods</h4>...

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Literature Corpus work
44776507-eda6-5684-a111-4791fb25842c
DOI
10.1101/2022.12.14.520462
Open publication

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