Article

Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of retinal detachment-related proliferative vitreoretinopathy

2022-11-08

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Purpose</h4> Proliferative vitreoretinopathy (PVR) is the most common cause of failure of retinal reattachment surgery and the molecular changes leading to this aberrant wound healing process is currently unknown. We aimed to study PVR pathogenesis using single-cell transcriptomics to dissect cellular heterogeneity in a rabbit PVR model. <h4>Methods</h4> PVR was induced unilater...

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Literature Corpus work: 0d166edb-a73d-5fe6-a803-47bcb1ffc2e4
DOI: 10.1101/2022.11.07.515504

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