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The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

25 Mar 2024

Abstract excerpt

Abstract The retinal pigment epithelium (RPE) maintains photoreceptor viability and function, completes the visual cycle, and forms the outer blood-retinal barrier (oBRB). Loss of RPE function gives rise to several monogenic retinal dystrophies and contributes to age-related macular degeneration. Retinal detachment (RD) causes separation of the neurosensory retina from the underlying RPE, disrupting the...

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PMID: 38528525
DOI: 10.1186/s12974-024-03062-2

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