Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predicting the progression of proliferative diabetic retinopathy: Pathophysiology, imaging phenotypes, and determinants of disease persistence despite therapy.

Survey of ophthalmology - 1 Jan 2026

Luu Brendan, van Dijk Elon H C, Hein Martin, An Dong, Yu Dao-Yi, Balaratnasingam Chandrakumar

Abstract excerpt

Proliferative diabetic retinopathy (PDR) is a leading cause of severe vision loss in working-aged adults and represents the end stage of chronic neurovascular injury in diabetes. Despite advances in screening and treatment, including panretinal photocoagulation (PRP), intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, and pars plana vitrectomy (PPV), outcomes remain heterogeneous: many eyes...

Read the complete abstract on PubMed

Topics

Humans
Diabetic Retinopathy
Disease Progression
Phenotype
Tomography, Optical Coherence
Fluorescein Angiography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Angiogenesis Inhibitors

Retinal Neovascularization

Source

Identifiers

PMID: 42314860
DOI: 10.1016/j.survophthal.2026.06.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predicting the progression of proliferative diabetic retinopathy: Pathophysiology, imaging phenotypes, and determinants of disease persistence despite therapy.PMID 42314860Read ↗

Nonproliferative retinopathy in diabetes type 2. Initial stages and characterization of phenotypes.Semantic proximity Read ↗

Characterization and relevance of different diabetic retinopathy phenotypes.Semantic proximity Read ↗

Retinal neurodegeneration in eyes with NPDR risk phenotypes: A two-year longitudinal study.Semantic proximity Read ↗

Advances in the Molecular Pathophysiology and Emerging Therapeutic Strategies for Diabetic RetinopathySemantic proximity Read ↗

Phenotypes and biomarkers of diabetic retinopathy.Semantic proximity Read ↗

Characterization of 2-Year Progression of Different Phenotypes of Nonproliferative Diabetic Retinopathy.Semantic proximity Read ↗

A proposal for early and personalized treatment of diabetic retinopathy based on clinical pathophysiology and molecular phenotyping.Semantic proximity Read ↗

Revisiting Retinal Degeneration Hallmarks: Insights from Molecular Markers and Therapy PerspectivesSemantic proximity Read ↗

Neuroinflammation and Neovascularization in diabetic eye diseases (DEDs): Identification of potential pharmacotherapeutic targetsSemantic proximity Read ↗

Global Prevalence of Diabetic Retinopathy Over the Last Decade (2015–2025): A Scoping ReviewSemantic proximity Read ↗

Remodeling of Retinal Architecture in Diabetic Retinopathy: Disruption of Ocular Physiology and Visual Functions by Inflammatory Gene Products and PyroptosisSemantic proximity Read ↗

Differential Distribution of Fibrovascular Proliferative Membranes in 25-Gauge Vitrectomy for Proliferative Diabetic RetinopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.