Article

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

2021-04-21

Abstract excerpt

<h4>ABSTRACT</h4> During embryonic development, cellular forces synchronize in space and time to generate functional tissue shapes. Apical constriction is one of these force-generating processes, and it is necessary to modulate epithelial curvature in fundamental morphogenetic events, such as neural tube folding. The emerging field of synthetic developmental biology proposes bottom-up approaches to examine the co...

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Literature Corpus work: 440156e8-c810-57b2-8dee-389e62f984e3
DOI: 10.1101/2021.04.20.440475

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