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Bioinspired Precision Engineering of Three‐Dimensional Epithelial Stem Cell Microniches

24 Apr 2020

Abstract excerpt

Maintenance of the epithelium relies on stem cells residing within specialized microenvironments, known as epithelial crypts. Two-photon polymerization (2PP) is a valuable tool for fabricating 3D micro/nanostructures for stem cell niche engineering applications. Herein, biomimetic gelatin methacrylate-based constructs, replicating the precise geometry of the limbal epithelial crypt structures (limbal stem cell...

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PMID: 32329968
DOI: 10.1002/adbi.202000016

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