Article

Genome-wide identification of binding sites of GRHL2 in luminal-like and basal A subtypes of breast cancer

2020-02-14

Abstract excerpt

Grainyhead like 2 (GRHL2) is one of three mammalian homologues of the grainyhead (GRH) gene. It suppresses the oncogenic epithelial-mesenchymal transition (EMT), acting as a tumor suppressor. On the other hand, GHRL2 promotes cell proliferation by increasing human telomerase reverse transcriptase (hTERT) activity, serving as a tumor promoter. According to gene expression profiling, breast cancer can be divided int...

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Literature Corpus work: 43311e60-51ac-582a-80c9-9bf28f40705d
DOI: 10.1101/2020.02.13.946947

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