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Article

Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression.

PloS one - 1 Jan 2012

Xiang Xiaoyu, Deng ZhongBin, Zhuang Xiaoying, Ju Songwen, Mu Jingyao, Jiang Hong, Zhang Lifeng, Yan Jun, Miller Donald, Zhang Huang-Ge

Abstract excerpt

Until now the essential transcription factor that determines the epithelial phenotype of breast cancer has not been identified and its role in epithelial-to-mesenchymal transition (EMT) and tumor progression remain unclear. Here, by analyzing large expression profiles of human breast cancer cells, we found an extraordinary correlation between the expression of Grainyhead transcription factor Grhl2 and epithelial...

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Identifiers

PMID: 23284647
DOI: 10.1371/journal.pone.0050781
PMCID: PMC3524252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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