Article
Genetics of Glioma Progression and the Definition of Primary and Secondary Glioblastoma
1997-10-01
Abstract excerpt
Summary Glioblastoma multiforme, the most malignant human brain tumor, may develop de novo (primary glioblastoma) or through progression from low‐grade or anaplastic astrocytoma (secondary glioblastoma). We present evidence that these subtypes of glioblastoma constitute distinct disease entities which evolve through different genetic pathways, affect patients at different age and are likely to differ in prognosis...
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Identifiers and source
- Literature Corpus work
- 42e48f9c-01cc-5e0d-ae3a-ad9489f12c25
- DOI
- 10.1111/j.1750-3639.1997.tb00993.x