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MOLECULAR PATHOLOGY OF MALIGNANT GLIOMAS

1 Feb 2006

Abstract excerpt

Malignant gliomas, the most common type of primary brain tumor, are a spectrum of tumors of varying differentiation and malignancy grades. These tumors may arise from neural stem cells and appear to contain tumor stem cells. Early genetic events differ between astrocytic and oligodendroglial tumors, but all tumors have an initially invasive phenotype, which complicates therapy. Progression-associated genetic...

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PMID: 18039109
DOI: 10.1146/annurev.pathol.1.110304.100043

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